The injury occurred following a collision with Mali goalkeeper Mamadou Samassa during the first half of the game played at the Grande Stade de Marrakech on Tuesday.
Following the incident, Nantes confirmed on Wednesday that the 28-year-old will miss the remainder of the season due to the injury.
This comes as a significant setback for the Canaries, who are currently fighting to avoid relegation in their domestic league.
Despite the challenges faced by Nantes this season, Simon has been a standout performer, contributing three goals and six assists in the current campaign.
His absence will undoubtedly be felt by the team as they strive to secure their position in the league.
Prior to his injury, the Nigerian had recently committed his future to Nantes by signing a new three-year contract.
